Green tea supplementation lowers insulin-like growth factor I in men at a high risk for prostate cancer

There is mounting evidence that increased circulating levels of insulin-like growth factor I (IGF-I) are associated with an increased risk of prostate cancer (CaP). Green tea (GT) supplementation significantly reduces circulating IGF-I levels in CaP patients and IGF-I levels and tumor development in the murine TRAMP model of CaP.