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Breastfeeding provides significant health benefits for mothers and infants, while postpartum depression (PPD) negatively impacts maternal well-being and child development. Using 2007 Oregon PRAMS data, we examined the association between breastfeeding for at least eight weeks and self-reported postpartum depressive symptoms (SRPPDS). Among 1,759 respondents, 13.5% reported SRPPDS and 72.2% breastfed for at least eight weeks. Mothers who breastfed less than eight weeks were 1.6 times more likely to report SRPPDS (95% CI: 1.004–2.57), adjusting for confounders. Stressful life events modified this association, with the strongest effect among women reporting no stressors. Findings suggest breastfeeding may reduce PPD risk.

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