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Abstract
Irritable Bowel Syndrome (IBS) affects 25–45 million Americans and significantly reduces health-related quality of life (HRQOL). This study examined illness representation using the Common Sense Model and its relationship to HRQOL in 101 adults with IBS, as well as the mediating role of catastrophizing coping style. Participants completed validated questionnaires assessing illness perceptions, coping, and HRQOL. Negative illness beliefs (e.g., chronicity, poor control, emotional impact) were associated with poorer HRQOL and greater catastrophizing, which in turn predicted lower HRQOL. Mediation analysis showed catastrophizing fully mediated the link between personal control and HRQOL. Findings highlight integrating illness beliefs and coping strategies into IBS management.