The long-term health effects of methamphetamine including cognitive impairments, anxiety, and depression, which can persist during recovery and are associated with poor treatment outcomes. Thus, biosignatures based on objectively quantifiable blood biomarkers that relate to neuropsychiatric data could be used clinically to monitor recovery. We previously identified seven plasma extracellular vesicle (EV) miRNAs that are differentially expressed in humans with active methamphetamine disorder (MA-ACT) vs. controls (CTL). Here we related the expression of plasma EVs and their miRNAs to measures of neuropsychiatric function.
Details
Title
Relationship between plasma extracellular vesicle miRNAs and measures of neuropsychiatric function in methamphetamine use disorder
Creator
Sandau, Ursula S. : Oregon Health and Science University Duggan, Erika : Oregon Health and Science University Smith, Sierra J. : Oregon Health and Science University Huckans, Marilyn : Oregon Health and Science University Nolan, John P. : Oregon Health and Science University Loftis, Jennifer M. : Oregon Health and Science University Saugstad, Julie A. : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2022