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Abstract

The greatest risk factor for developing Parkinson's disease is aging, and the accumulation of reactive oxygen species is thought to play a significant role in the aging process. Glutathione is a universal antioxidant in animals and plants that helps maintain redox homeostasis within cells, preventing or delaying excessive buildup of reactive oxygen species that may damage or destroy the cell. The work presented in this thesis adds to our understanding of how glutathione affects the aging process and its therapeutic potential in aging-related neurodegenerative diseases like Parkinson's disease.

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