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1.
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Gene transcription is fundamental in establishing and maintaining cell identity and function. All normal cells are encoded with the same DNA, so transcription is essentia [...]
2024-02-23 |
Dissertation |
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2.
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The HER2+ subtype of breast cancer typically results from amplification of the proto-oncogene ERBB2, that causes overexpression of the mitogenic cell surface receptor kin [...]
2017 |
Dissertation |
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3.
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4.
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Treating viral upper respiratory infections (URI) with antibiotics contributes to the rise of antimicrobial resistance. Major drivers of unnecessary prescribing are a pat [...]
2020 |
Abstract |
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5.
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The majority of gastrointestinal stromal tumor (GIST) are driven by mutations in KIT or platelet derived growth factor receptor alpha (PDGFRA) receptor tyrosine kinases. [...]
2022 |
Abstract |
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6.
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Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the GI tract. The second most common type of GIST is driven by oncogenic mutations in PDGFRA, of which [...]
2021 |
Abstract |
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7.
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8.
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9.
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Preponderant genomic sequencing and clinical evidence have revealed the remarkable heterogeneity that underpins leukemia. Such efforts have brought to the forefront new o [...]
2021 |
Dissertation |
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10.
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Abnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully [...]
2020 |
Abstract |
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