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1.	PDF Flynn.Patrick.2024 Bloodlines matter: leukemia associated mutation FLT3-ITD disrupts dendritic cell homeostasis and leads to altered T cell phenotypes Flynn, Patrick Dendritic cells (DC) are mediators between innate and adaptive immune responses to pathogens and tumors. DC development is determined by signaling through the receptor ty [...] 2024-02-24 \| Dissertation \| Detailed record - Similar records
2.	PDF ResearchWeek.2023.Klocke.Christopher Identification of cellular interactions in the tumor immune microenvironment underlying CD8 T cell exhaustion Klocke, Christopher ; Moran, Amy ; McWeeney, Shannon ; Adey, Andrew[...] Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...] 2023-08-18 \| Abstract \| Detailed record - Similar records
3.	PDF ResearchWeek.2023.Sullivan.Jennifer A novel computational framework for inferring the developmental and cellular origins of rare and congenital disorders using scRNA-seq data Sullivan, Jennifer ; Adey, Andrew ; Schweitzer, Ronen ; McWeeney, Shannon[...] Despite their devastating impacts on millions of people, most rare and congenital disorders remain poorly understood, leaving the patients with these disorders with no FD [...] 2023-07-20 \| Abstract \| Detailed record - Similar records
4.	PDF ResearchWeek.2020.Egger.Julian Transcriptome-wide characterization of alternative splicing variants in drug resistant AML Egger, Julian ; Zheng, Christina ; McWeeney, Shannon ; Wu, Guanming[...] Abnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully [...] 2020 \| Abstract \| Detailed record - Similar records

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