Acute myeloid leukemia (AML) is a form of blood cancer which mostly affects older people and undesirable outcomes of standard chemotherapy approaches are [...]

Proactive mentorship and professional development are fundamental to the success of early career faculty. The Early Career Advancement Program (ECAP) within the OHSU Scho [...]

In this work, I explored epigenetic dysregulation AML by Chromatin dynamics in acute myeloid leukemia subsets defined by genetic and drug response diversity and the ident [...]

Single-cell technologies have created a new taxonomic challenge: to create a shared language for defining individual cells within complex organisms. In this work, I compl [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

Current treatments for FTD mitigate some behavioral changes, but there are no therapies that prevent or slow the progression of the disease. Profiling the epigenetic chan [...]

Each developmental lineage that gives rise to a complete organism is created through a unique network of regulatory interactions. While reverse engineering each of these [...]

This novel computational framework for the analysis of single-cell gene expression data from human tumor samples enables the identification of molecular activity associat [...]

Despite their devastating impacts on millions of people, most rare and congenital disorders remain poorly understood, leaving the patients with these disorders with no FD [...]