Tissue-resident memory T cells (TRM) are enriched in nonlymphoid barrier organs where they typically reside long-term without recirculating. These cells are functionally [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

The tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC) is characterized by restrained function of effector T cells and provides resistance to immunot [...]