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Bone defects may occur after trauma, infection, or oncologic resection. Autologous bone grafting is the current treatment option; however, grafting is limited in the case [...]

The extracellular matrix (ECM) plays a governing role in regulating functional cell and tissue behavior through biochemical and biophysical signaling. Ongoing tissue engi [...]

Ossification is a developmental process where bone is created in appositional layers through the gradual calcification of the native extracellular matrix (ECM). This evol [...]

The extracellular matrix (ECM) plays a governing role in regulating functional cell and tissue behavior through biochemical and biophysical signaling. Ongoing tissue engi [...]

Tumors overexpressing the HER2 oncogene account for around 20% of breast cancer cases and are associated with aggressive disease. These tumors generally originate from a [...]