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The bone tissue is a complex nanocomposite, organized in a calcified extracellular matrix. Bone autografts remain the gold standard to treat traumatic bone injuries. Howe [...]

Bone tissue is a common site of metastasis, affecting a large number of patients with advanced cancer. The specificity of bone for extravasation of many types of cancers [...]

Bone defects may occur after trauma, infection, or oncologic resection. Autologous bone grafting is the current treatment option; however, grafting is limited in the case [...]

The leading cause of failure for current bone replacements is a lack of vascularization. Ideal synthetic bone scaffolds provide structural rigidity, allow cellular migrat [...]

Cardiovascular disease affects nearly half of all U.S. adults and is the leading cause of death worldwide. Advanced cases are often treated through vascular grafting to b [...]

Ossification is a developmental process where bone is created in appositional layers through the gradual calcification of the native extracellular matrix (ECM). This evol [...]

Bone defects can occur after trauma, infection, or oncologic resection and autologous bone grafting is the current treatment option. However, this method has its limitati [...]

Research builds a foundation of scientific and clinical knowledge used to improve oral health and overall health. At the OHSU School of Dentistry, research is a signif [...]

This inaugural issue includes articles from Dr. Ana Fugolin, D.D.S., M.S, Ph.D. and Dr. Jonathan Baker, Ph.D., based on summaries of their research at the Oregon Health & [...]

The use of synthetic mRNA-based gene modification offers several advantages over traditional DNA based gene therapy including faster translational kinetics, transient exp [...]