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Neuroinflammation and mitochondrial dysfunction are early events in Alzheimer’s disease (AD) and contribute to neurodegeneration and cognitive impairment. The CD74-MIF (m [...]
2023-07-25 |
Abstract |
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Mitochondria are essential organelles for all cell types, especially for neurons, which possess extremely long axons that require the support of mitochondria from cell bo [...]
2021 |
Dissertation |
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Placental mitochondrial respiration is impacted by obesity, type 2 gestational diabetes (A2GDM), and fetal sex. The mechanism of metformin, a "GDM treatment," is unclear, [...]
2020 |
Abstract |
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Lewy bodies comprised of aggregated alpha synuclein (αSyn) protein are a pathological hallmark of the Parkinson's disease (PD). Increased oxidative stress, mitochondrial [...]
2020 |
Abstract |
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Long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) and trifunctional protein (TFP) deficiencies are inherited disorders of long-chain fatty acidmetabolism caused by mutat [...]
2018 |
Thesis |
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The goal of this dissertation is to improve understanding and treatment for the chorioretinopathy seen in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) p [...]
2024-06-13 |
Dissertation |
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