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Acute kidney injury (AKI) is a widespread health problem, with increased incidence among hospitalized patients. The most common cause of AKI is ischemic injury, which tar [...]

Cardiorenal syndrome type 1 (CRS1) is acute kidney injury (AKI) due to rapid worsening of cardiac function, and is a common cause of AKI. Ischemic AKI and subsequent chro [...]

Acute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are un [...]

Angiotensin converting enzyme 2 (ACE2) is a key regulator of the renin angiotensin system (RAS) that acts by degrading angiotensin II (AngII). Within the kidney, ACE2 is [...]

Clinicians, like every other human, are not good prognosticators. With the ever- increasing complexity of healthcare, the inherent limitations of the human brain, and a [...]

Destruction of skeletal muscle (rhabdomyolysis) releases myoglobin, causing rhabdomyolysis-induced acute renal injury (rhAKI). As rhAKI commonly occurs in austere environ [...]

Causal inference methods play a vital role in health sciences research, requiring robust methodologies for treatment evaluation and clinical decision-making. Propensity S [...]

Patients requiring extracorporeal membrane oxygenation (ECMO) support often experience acute kidney injury (AKI) as a result of their inciting illness and are at high ris [...]