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This dissertation describes the implementation of a technique for using cellular miRNAs as tools for the discovery of virus-host interactions. With this methodology, I di [...]

Over the last few decades, the utility of viral vectors has expanded from their initial use as clinical therapeutics for debilitating genetic diseases to include their us [...]

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes acute febrile illness and long-lasting joint and muscle pain. The 2013-2016 CHIKV outbreaks in the Am [...]

Alphaviruses are arthropod-transmitted RNA viruses, including the NIAID Category B priority pathogens Eastern equine encephalitis (EEEV), Venezuelan equine encephalitis ( [...]