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One of the most important tools for diagnosis, analysis, and study of cancer tissues is immunolabeling. Simultaneously analyzing both expression and spatial data of key s [...]

Cancer is one of the leading causes of rate mortality worldwide.[1-3] Early treatment of the cancer can significantly reduce the mortality.[4] Pancreatic Ductal Adenocarc [...]

HER2-positive breast cancer is an aggressive subtype of breast cancer with patients having significantly lower survival rates compared to other breast cancers. HER2-posit [...]

Early phase oncology trials often require a continuous safety monitoring because of the unexpected toxicity associated with investigational agents. Safety monitoring beco [...]

Tissue-resident memory T cells (TRM) are enriched in nonlymphoid barrier organs where they typically reside long-term without recirculating. These cells are functionally [...]

This thesis work highlights development and applications for both circulating extracellular vesicles (EV) and cell-free RNA (cf-RNA) toward liquid biopsy based early canc [...]

The inability to develop an effective anti-tumor immune response plays a key role in cancer progression. Patients with a strong anti-tumor T cell response, indicated by i [...]

Metastatic spread of cancer is responsible for the vast majority of cancer-related deaths highlighting the need to better understand the cellular mechanisms underlying th [...]