The Bcr‑Abl tyrosine kinase drives chronic myeloid leukemia (CML) and is the target of imatinib therapy, which induces complete cytogenetic responses in most patients. Ho [...]

White matter injury (WMI) contributes substantially to neurological impairment after ischemic stroke. However, WMI is often ignored in stroke therapeutic developments lea [...]

Long-term potentiation (LTP) relies on coordinated kinase activity, including CaMKII and ERK, to regulate synaptic strength through AMPA receptor function and trafficking [...]

Rod bipolar cells (RBCs) are the first interneurons in the primary rod visual pathway. RBCs transmit light-driven signals from rods in the outer retina and contribute to [...]

The human placenta is the primary life-support organ for the developing fetus. It integrates a multi-organ system's functions but comprises only five major cell types. It [...]

This dissertation describes my work on two main projects, first to expand and calibrate a site-directed fluorescence labeling method that can assess distance relationshi [...]