This dissertation presents deep learning frameworks for automated retinal biomarker quantification and AMD severity staging using volumetric OCT and OCTA. The work includ [...]

Rod bipolar cells (RBCs) are the first interneurons in the primary rod visual pathway. RBCs transmit light-driven signals from rods in the outer retina and contribute to [...]

Light input from the retina entrains the circadian clock in the suprachiasmatic nucleus via melanopsin‑expressing intrinsically photosensitive retinal ganglion cells (ipR [...]

Technological changes to modern society have lead to circadian misalignment in a significant portion of the population, resulting in numerous metabolic, sleep, [...]

During development, specific combinations of molecular cues guide the proper formation of neural circuits. Neuronal migration, axon guidance, and synapse [...]

The retina is tasked with detecting light from the environment, and transmitting that visual information as an electrical signal to the brain. Visual signals are highly [...]

This dissertation showcases three independent studies that address various unknown aspects of a paraneoplastic syndrome called melanoma-associated retinopathy (MAR). Thro [...]

Dr. David Huang is a Professor of Ophthalmology and Biomedical Engineering in the School of Medicine, an Associate Director & Director of Research at Casey Eye Instit [...]

Of the over 100 types of retinal neurons, amacrine cells account for 60 types representing the bulk of this diversity, with each of the roughly 60 types receiving a diffe [...]