This thesis focuses on acid‑sensing ion channels (ASICs), with particular attention to their mechanisms of activation and desensitization. ASICs are proton‑gated ion chan [...]

Methamphetamine-associated heart failure (MethHF) is quickly becoming a recognized healthcare problem with devastating patient and societal impact, especially in the stat [...]

The goal of my PhD has been to develop and adapt optical chemical biology approaches to study signal transduction in cells. I developed genetically encoded FRET sensors t [...]

Myc family proteins, including N-Myc, are key regulators of proliferation and differentiation, with N-Myc overexpression driving neuroblastoma progression. This work inve [...]

Technological changes to modern society have lead to circadian misalignment in a significant portion of the population, resulting in numerous metabolic, sleep, [...]