1.
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Dendritic cells (DC) are mediators between innate and adaptive immune responses to pathogens and tumors. DC development is determined by signaling through the receptor ty [...]
2024-02-24 |
Dissertation |
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2.
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In this dissertation, the rhesus macaque embryo was evaluated for aneuploidy frequency to determine if it is a suitable translation model to study human embryology. Using [...]
2017 |
Dissertation |
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3.
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Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]
2023-08-18 |
Abstract |
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4.
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Uveal melanoma (UM) is a rare but aggressive disease, with >50% of tumors propagating metastatic disease spread - associated with nearly uniform fatality. Despite sign [...]
2021 |
Abstract |
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5.
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Cell-cell co-occurrence patterns are critical in shaping biological and clinical phenotypes, but existing tools for analyzing single-cell RNA sequencing (scRNA-seq) data [...]
2025-03-10 |
Thesis |
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6.
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Despite their devastating impacts on millions of people, most rare and congenital disorders remain poorly understood, leaving the patients with these disorders with no FD [...]
2023-07-20 |
Abstract |
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7.
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This dissertation quantitatively assesses the single-cell spatial landscape of the tumor microenvironment for three cancer types. Statistical and machine learning approac [...]
2024-03-22 |
Dissertation |
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8.
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Triple Negative Breast Cancer (TNBC) is a complex malignancy subtype which commonly forms aggressive tumors with substantial stromal involvement. Unlike the Luminal and H [...]
2024-12-16 |
Thesis |
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9.
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Immune checkpoint inhibitor (ICI) therapies, such as anti-PD1 and anti-CTLA4, have proved to be clinically effective in numerous malignant diseases due to their ability t [...]
2024 |
Abstract |
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10.
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Despite tremendous advances in knowledge of most of the organs in our bodies, tendons largely remain a mystery. Yet tendons are implicated in a number of disorders, inclu [...]
2020 |
Abstract |
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