Coronary artery disease, a leading cause of death in the United States, is commonly treated with arterial stents. Common issues with cobalt chromium (CoCr) and stainless- [...]

Work in this thesis characterizes the cellular phenotype of a novel progenitor-derived endothelial-like cell, two in vivo assessments of bioprosthetic venous valve endo [...]

Small-diameter vascular grafts remain a critical unmet need due to limitations of autologous vessels and synthetic grafts. This work investigates the role of extracellula [...]

Cardiovascular disease affects nearly half of all U.S. adults and is the leading cause of death worldwide. Advanced cases are often treated through vascular grafting to b [...]

Cardiovascular diseases (CVD) such as ischemic heart disease and peripheral artery disease, continue to be the leading cause of death worldwide. The primary underlying ca [...]

This dissertation focuses on the development of metrological techniques to study the mechanisms of thrombosis and hemostasis, processes essential for stopping bleeding bu [...]

Hemostasis is the process of sealing a vascular leak through concomitant activation of the blood coagulation cascade and blood platelet adhesion to and activation by the [...]

The prevention and treatment of cardiovascular disease complications, including occlusive blood clots responsible for heart attacks and strokes, are projected to cost A [...]

The clinical standard for small diameter vessel treatment, currently, is the use of autologous vessels. However, due to limited availability and pre-surgical complication [...]