This work explores the structure and function of an important copper monooxygenase: peptidylglycine alpha-amidating monooxygenase. The canonical reaction mechanism of thi [...]

The Blackburn Lab studies biological copper chemistry using biochemical, biophysical, and advanced spectroscopic techniques. Our research aims are two-pronged, which is r [...]

This dissertation describes the structural characterization of peptidylglycine monooxygenase (PHM). PHM belongs to a unique class of enzymes: the mononuclear dicopper m [...]