The goal of my PhD has been to develop and adapt optical chemical biology approaches to study signal transduction in cells. I developed genetically encoded FRET sensors t [...]

Poly-(ADP)-ribose polymerases (PARPs) are a family 17 enzymes in humans that have diverse roles in cell biology including innate immune response, DNA repair, and regulati [...]

Biological imaging relies on the ability to generate contrast between the target of interest and the cell. Proteins are specifically labeled with reporters compatible wit [...]

Terrell Hill's book, Free Energy Transduction and Biochemical Cycle Kinetics, is one of the most important introductory-level contributions to the biophysics of molecular [...]

To collect information which would aid in our understanding of normal immune responses to microbes of the body flora, lymphocyte transformation studies were done on a rep [...]