Asthma is characterized by airway hyperreactivity, an abnormal tendency for airways to constrict. Maternal asthma increases the risk of childhood asthma more than paterna [...]

Obese asthmatic patients often have severe symptoms and poor responses to treatment. The molecular mechanisms of obesity-related asthma and associated airway hyperreactiv [...]

The neuronal M2 muscarinic receptor is a G protein-coupled receptor expressed in parasympathetic nerves that provides negative feedback for acetylcholine release. Dysfunc [...]

Children born to obese mothers are at a higher risk of developing asthma, but the underlying mechanisms are unclear. We used a diet-induced maternal obesity mouse model t [...]

Diagrams showing trachea, bronchial tubes, bronchioles, and bronchial asthma - unattributed, likely Ito