The prevention and treatment of cardiovascular disease complications, including occlusive blood clots responsible for heart attacks and strokes, are projected to cost A [...]

Cancer is a hypercoagulable state. Thrombosis is the second leading cause of death in cancer, and development of thrombosis confers a worse prognosis for patients with [...]

Lipopolysaccharide (LPS), the major outer wall component of Gram-negative bacteria, plays a critical role in the pathogenesis of sepsis and are known to contribute to the [...]

The prevention of bleeding and protection of the vascular wall integrity is mediated by the blood cells platelets and enzymatic coagulation reactions in a process called [...]

The formation of a hemostatic plug to staunch blood loss at sites of vascular injury relies on the dynamical processes of activation of the coagulation cascade and platel [...]

The blood microenvironment is a dynamic system consisting of a diverse range of cells and plasma proteins that function together to maintain homeostasis. In my dissertati [...]