The clinical standard for small diameter vessel treatment, currently, is the use of autologous vessels. However, due to limited availability and pre-surgical complication [...]

Platelets are the first defenders of vascular integrity, responding to vascular injury in a regulated sequence of adhesion, activation, and aggregation that enables form [...]

Pathological thrombosis is a significant driver of human morbidity and mortality today. Overall, this dissertation presents a study of the pathophysiology, clinical manag [...]

Formation of a hemostatic clot is essential for minimizing blood loss upon injury and is mediated, in part, by tightly regulated activity of and crosstalk between platele [...]

Hemostasis is the process of sealing a vascular leak through concomitant activation of the blood coagulation cascade and blood platelet adhesion to and activation by the [...]

Coronary artery disease, a leading cause of death in the United States, is commonly treated with arterial stents. Common issues with cobalt chromium (CoCr) and stainless- [...]

Cardiovascular disease affects nearly half of all U.S. adults and is the leading cause of death worldwide. Advanced cases are often treated through vascular grafting to b [...]

Cardiovascular diseases (CVD) such as ischemic heart disease and peripheral artery disease, continue to be the leading cause of death worldwide. The primary underlying ca [...]