Chronic stress–driven sympathetic signaling influences cancer development by reshaping the tumor microenvironment (TME). This dissertation reviews how sympathetic nerves [...]

Illness behaviors, metabolic disturbances, and cognitive injury are common in cancer patients and frequently lead to wasting or cachexia. This devastating state of malnut [...]

Acute Myelogenous Leukemia (AML) is an aggressive cancer of the bone marrow that affects both adults and children alike. While many patients achieve remission following i [...]

Disease is an ever-present threat to the survival of the individual. To meet these challenges, higher organisms have developed complex mechanisms designed to heal and fig [...]

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of malignancies, with a dismal survival rate and limited treatment options. Advances in therapeutic modalit [...]

Cachexia is a devastating syndrome with cardinal features of anorexia, weight loss, and fatigue. This syndrome occurs during numerous chronic diseases, such as cancer, ci [...]

Asthma is characterized by airway hyperreactivity, an abnormal tendency for airways to constrict. Maternal asthma increases the risk of childhood asthma more than paterna [...]

Cachexia, characterized by muscle loss, reduced food intake, and decreased activity, is a common complication of chronic diseases such as cancer, renal failure, heart fai [...]

Disorders of food intake and energy homeostasis commonly accompany acute and chronic disease and are thought to result from proinflammatory cytokine signaling in the brai [...]