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Is the capacity of Mtb-specific CD4+ and CD8+ T cells to produce three key Th-1 cytokines compromised among Ugandan children with TB as compared to Ugandan adults with TB [...]
2023 | Scholarly project capstone (M.D.) |
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MR1-restricted T (MR1T) cells are part of a growing class of unconventional T cells that have emerged as important players in the early response to microbial infection. T [...]
2019 | Dissertation |
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Immune checkpoint blockade (ICB) therapy targets checkpoint proteins to restore normal function to the immune system so that it can attack cancer cells. It is used succes [...]
2024 | Abstract |
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Immune checkpoint blockade (ICB) has revolutionized the ways in which we treat some cancers, producing durable responses. However, many patients fail to respond to ICB. I [...]
2023-08-16 | Dissertation |