1.
|
Atherosclerosis is the leading cause of cardiovascular disease, accounting for nearly 30% of deaths in the United States. Patients with late-stage atherosclerosis suffer [...]
2022 |
Dissertation |
|
2.
|
Protein tyrosine kinases play an essential role within cells, transmitting signals to propagate a variety of fundamental cell functions. The activity of tyrosine kinases [...]
2003-06-01 |
Dissertation |
|
3.
|
Successful cancer treatment continues to elude modern medicine and its arsenal of therapeutic strategies. Therapy resistance is driven by tumor heterogeneity, complex int [...]
2020 |
Abstract |
|
4.
|
Certain cancers, including gastrointestinal stromal tumor (GIST) and subsets of melanoma, are caused by somatic KIT mutations that result in constitutive KIT receptor tyr [...]
2017 |
Dissertation |
|
5.
|
|
6.
|
|
7.
|
This dissertation investigates the functional significance and therapeutic implications of novel extracellular domain (ECD) alterations in PDGFRA found in glioma. Specifi [...]
2025-04-25 |
Dissertation |
|
8.
|
Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide, with high morbidity, high mortality, and few therapeutic options outside of surgery [...]
2017 |
Dissertation |
|
9.
|
The majority of gastrointestinal stromal tumor (GIST) are driven by mutations in KIT or platelet derived growth factor receptor alpha (PDGFRA) receptor tyrosine kinases. [...]
2022 |
Abstract |
|
10.
|
|