In this oral history interview, Kent Thornburg, Ph.D,, explores his career in cardiovascular and developmental health research at OHSU. He discusses the significant influence of his father and other mentors throughout his education. Thornburg, who joined OHSU in 1971, highlights his contributions to cardiovascular physiology and the establishment of OHSU’s Heart Research Center. His collaboration with epidemiologist Dr. David Barker shifted his research focus onto the influence of prenatal nutrition and stress on lifelong health and led to the creation of the Center for Developmental Health. Later, a collaboration with the founder of Bob’s Red Mill led to the creation of the Bob and Charlee Moore Institute for Nutrition & Wellness. Looking ahead, Thornburg emphasizes the role of epigenetics and personalized medicine in shaping the future of healthcare.