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Abstract

Type 1 diabetes (T1D) is a chronic disease where the pancreas does not produce sufficient insulin. Exogenous insulin is required to be delivered. Over delivery of insulin can cause hypoglycemia, which can cause coma or death if not treated. Under delivery can cause hyperglycemia; long-term exposure can cause chronic health problems including neuropathy, retinopathy, and limb loss. Model predictive control (MPC) is a state-of-the-art method for controlling glucose levels in people with T1D. There is currently not an adaptive MPC for single and dual-hormone AP control systems that can effectively handle exercise.

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