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In this work, I explored epigenetic dysregulation AML by Chromatin dynamics in acute myeloid leukemia subsets defined by genetic and drug response diversity and the ident [...]
2022 |
Dissertation |
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Acute Myelogenous Leukemia (AML) is an aggressive cancer of the bone marrow that affects both adults and children alike. While many patients achieve remission following i [...]
2020 |
Dissertation |
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Genetic heterogeneity makes clinical interventions challenging for patients with acute myeloid leukemia (AML). Identifying and targeting common microenvironment-driven pa [...]
2022 |
Dissertation |
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Contributing to proteomic diversity, alternative splicing of pre-mRNA is widespread in the human transcriptome and can greatly influence regulation of both normal and dis [...]
2020 |
Dissertation |
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Acute Myeloid Leukemia (AML) is a genetically and phenotypically heterogeneous white blood cell cancer with a poor prognosis and limited therapeutic options. For many dec [...]
2022 |
Dissertation |
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