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1.
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Myelin ensheaths axons and increases their conduction velocities. In the central nervous system (CNS) myelin is produced by oligodendrocytes (OLs) that differentiate from [...]
2020 |
Abstract |
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2.
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The RNA sensor RIG-I (retinoic-acid inducible gene 1), also known as DDX58, recognizes cytosolic short dsRNA and plays a major role in the antiviral response. RIG-I activ [...]
2020 |
Abstract |
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3.
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The ability of tumors to induce immunosuppression and inhibit the cytolytic function of tumor-infiltrating lymphocytes (TIL) is a major obstacle to creating effective imm [...]
2020 |
Dissertation |
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4.
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The follicle is the structural unit within the ovary where endocrine-acting sex steroids and hormones are synthesized and the development of a mature oocyte capable of be [...]
2020 |
Dissertation |
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6.
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7.
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8.
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This dissertation presents novel evidence that PTPN11 is activated by an upstream kinase, TNK2. PTPN11-mutant JMML and AML primary patient cells have displayed significan [...]
2017 |
Dissertation |
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9.
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Polymorphonuclear leukocytes, specifically neutrophils, are highly dynamic, multi-functional innate immune cells. Neutrophils are among the first cellular responders to b [...]
2017 |
Dissertation |
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10.
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Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide, with high morbidity, high mortality, and few therapeutic options outside of surgery [...]
2017 |
Dissertation |
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