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Women are impacted twice as likely as men by urgency urinary incontinence (UUI) with nearly one-third of women suffering from UUI in their lifetime. The etiology of UUI i [...]

The development of biofilms on dental restorations may lead to the formation of secondary caries. The purpose of this study was to determine the efficacy of bioactive sma [...]

Interferon (IFN) family cytokines stimulate a broad group of genes known as interferon stimulated gene (ISGs). The primary function of ISGs is to provide antiviral host d [...]

The oral microbiome has co-evolved and coexisted in a symbiotic relationship within their own ecology and with the host. Understanding the oral ecosystem and how it promo [...]

The gut microbiome is involved in promoting or inhibiting (protecting against or contributing to the development of) many diseases, such as diabetes, inflammatory bowel d [...]

We developed a workflow for quantitative microbiome profiling to quantify bacterial abundance using a known mock microbial dilution series.

Recently, longitudinal changes in human gut microbiome composition have been proposed to be more robust markers of host health than cross-sectional variation. However, it [...]

Here we evaluated the accuracy of several freely available software packages to correct for variable gene copy numbers in microbiome profiling using the 16S rRNA gene. We [...]

There is growing appreciation for the role that commensal microorganisms play in affecting host health and disease, especially in humans. Comprised of bacteria, fungi, vi [...]

Culture-independent methods are changing the way scientists interrogate microbes in complex environments such as the human body. Specifically, targeted sequencing of the [...]