1.
Due to the complexity of BCR/ABL-independent TKI resistance, a central question is whether relapse acts through the canonical BCR/ABL CML pathways seen in dependent cases [...]
2017 | Thesis |
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Two major obstacles persist in the fight against cancer: its heterogeneity and its ability to adapt. Cancers originating from a specific organ system can have various var [...]
2013 | Thesis |
4.
Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide, with high morbidity, high mortality, and few therapeutic options outside of surgery [...]
2017 | Dissertation |
5.
Sarcoma is a cancer arising in the bone, connective, or soft-tissue and occurs at any age. Among these, spindle cell rhabdomyosarcoma (SCR) is a rare, aggressive skeletal [...]
2020 | Abstract |
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Genetic aberrations that cause constitutive activation of the receptor tyrosine kinase (RTK), ROS1, can drive cancer formation. Treatment of these cancers with tyrosine k [...]
2022 | Dissertation |