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Analyzing and reporting data generated from cDNA microarray experiments is a challenging process. There are many potential sources of error that must be controlled to obt [...]

Immune checkpoint blockade (ICB) therapy targets checkpoint proteins to restore normal function to the immune system so that it can attack cancer cells. It is used succes [...]

Mass spectrometry has become a vital tool in the field of proteomics. This technique enables the study of proteins on a much larger scale, facilitating further biological [...]

Pioneer neurons establish the initial nervous system structure by extending axons toward distant targets, but their molecular distinction from follower neurons was previo [...]

Patient stratification is essential for addressing breast cancer's inter- and intra-heterogeneity. While the PAM50 classifier is widely regarded to be the gold standard f [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

Uveal melanoma (UM) is a rare but aggressive disease, with >50% of tumors propagating metastatic disease spread - associated with nearly uniform fatality. Despite sign [...]

Ionizing radiation (IR) is frequently used in the treatment of cancer through radiation therapy. However, exposure to IR also poses a significant safety risk for nuclear [...]

Cell-cell co-occurrence patterns are critical in shaping biological and clinical phenotypes, but existing tools for analyzing single-cell RNA sequencing (scRNA-seq) data [...]

Microarray gene expression research frequency generates large numbers of questions or information needs throughout the course of the experiment. Many of these questions r [...]