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1.
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This cancer cell-intrinsic GOT2-PPARδ axis promotes spatial restriction of both CD4+ and CD8+ T cells from the tumor microenvironment, and fosters the immune-suppressive [...]
2021 |
Dissertation |
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2.
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Mechanisms of immune suppression in peripheral tissues counteract protective immu-nity to prevent immunopathology and are coopted by tumors for immune evasion. Blood and [...]
2019 |
Dissertation |
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3.
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4.
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5.
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Malignant brain tumors remain incurable and improving outcomes will require personalized treatment strategies. In personalized medicine, therapeutics are tailored to each [...]
2019 |
Dissertation |
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6.
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Colorectal cancer (CRC) is the 3rd most prevalent cancer worldwide. In treating cancer, the tumor microenvironment has a large impact on cell behavior, growth, and tumor [...]
2024 |
Abstract |
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7.
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Leukocytes recruited to and persistent within chronically inflamed tissues play critical roles in fostering neoplastic progression. Immunotherapies designed to reprogram [...]
2019 |
Dissertation |
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8.
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A dissertation discussing the role of mesenchymal kit ligand (kitl) in the pancreas, specifically in regards to healthy tissue homeostasis, tissue architecture, and disea [...]
2025-03-21 |
Dissertation |
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9.
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The HER2+ subtype of breast cancer typically results from amplification of the proto-oncogene ERBB2, that causes overexpression of the mitogenic cell surface receptor kin [...]
2017 |
Dissertation |
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10.
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The inability to develop an effective anti-tumor immune response plays a key role in cancer progression. Patients with a strong anti-tumor T cell response, indicated by i [...]
2016-09-01 |
Thesis |
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