Amyotrophic Lateral Sclerosis is the most common adult onset motor neurodegenerative disease. The etiology of the disease remains obscure, and as such there is no effecti [...]

Neuronal remodeling is a crucial step towards healthy maturation of synapses, circuits and eventually brain function. This process involves changes in neuron morphology s [...]

Glial cells are critical for maintaining a healthy nervous system. Key regulatory functions include synaptic remodeling, metabolic support of neurons, and protective immu [...]

Drosophila melanogaster contains a single small-conductance Ca²⁺‑activated K⁺ (SK) channel gene most closely related to mammalian SK1, a channel that has proven difficult [...]

This thesis presents the findings of a subpopulation analysis of The Food Pharmacy Study at OHSU KCVI, a randomized controlled trial aiming to assess the role a fruit and [...]

This randomized controlled feasibility study evaluated a team-based, peer-led curriculum promoting nutrient-rich diets and physical activity during pregnancy to reduce ge [...]

Axons can represent the majority of a neuron's volume and are energetically demanding. Specialized glia ensheathe axons to insulate them and are believed to support axon [...]

Current treatments for FTD mitigate some behavioral changes, but there are no therapies that prevent or slow the progression of the disease. Profiling the epigenetic chan [...]