Opioid Use Disorder (OUD) is an ongoing epidemic that effects millions of individuals worldwide. There is limited research on OUD in patients with cancer and standardized [...]

Cancer-related pain is ubiquitous. Targeted procedural interventions may be an important and under-utilized method for improving cancer-related pain and quality of life. [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

Liquid biopsy provides a minimally-invasive alternative to solid tissue biopsy for assessing tumor-derived molecules such as circulating tumor DNA (ctDNA). Detection and [...]

Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the GI tract. The second most common type of GIST is driven by oncogenic mutations in PDGFRA, of which [...]

As a part of the Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) precision medicine cancer trial, serial biopsies from cancer patients ar [...]

Abnormal splicing events can promote drug resistance in a variety of cancer types, however, the full extent of genome-wide splicing in therapy-resistant AML is not fully [...]

Recent research shows that microRNAs (miRNAs) may be potential biomarkers of cancer. MiRNAs are noncoding RNA molecules that regulate gene expression in the post-transcri [...]

PIN1 is a phosphorylation-directed member of the peptidyl-prolyl cis/trans isomerase family that facilitates conformational changes in phosphorylated targets such as c-MY [...]

Nationwide efforts are engaging communities in large genetic studies to better estimate the population-wide prevalence of some heritable cancers that have medical recomme [...]