Advancing precision medicine in the treatment of cancer is complex and requires extensive molecular profiling to identify therapeutic targets and appropriately stratify p [...]

The mechanisms that regulate gene expression are complex, however many features have been well-conserved through evolution. This dissertation discusses three main topic [...]

One-third of cardiomyocyte are lost just before birth. We studied the role of endoplasmic reticulum (ER) stress response in cardiomyocyte apoptosis in perinatal sheep hea [...]