Myelination in the CNS is essential for neuronal function, and oligodendrocytes achieve this by wrapping axons with multilayered myelin sheaths. We identify FBXW7 as a ke [...]

Myelin ensheaths axons and increases their conduction velocities. In the central nervous system (CNS) myelin is produced by oligodendrocytes (OLs) that differentiate from [...]

Oligodendrocytes are specialized central nervous glia that progress through distinct cellular stages, each with its own specific morphological features, specific proteins [...]