The prevention of bleeding and protection of the vascular wall integrity is mediated by the blood cells platelets and enzymatic coagulation reactions in a process called [...]

Lipopolysaccharide (LPS), the major outer wall component of Gram-negative bacteria, plays a critical role in the pathogenesis of sepsis and are known to contribute to the [...]

What keeps us from bleeding out when we scrape our knee or sustain severe injuries? As we speak, the coagulation cascade, an intricate and highly regulated cascade of pro [...]

Trauma-induced coagulopathy (TIC) is a complex process of dysfunctional and/or abnormal clot function occurring in up to 25% of patients presenting with severe bleeding a [...]

Platelets are the first defenders of vascular integrity, responding to vascular injury in a regulated sequence of adhesion, activation, and aggregation that enables form [...]