Freezing of gait (FOG) is one of the most debilitating features of Parkinson’s disease (PD). FOG may be due to a lack of central inhibition, as people with PD and FOG (PD+FOG) have difficulty inhibiting postural preparation prior to initiating stepping. We recently demonstrated that presynaptic inhibition (PSI) in the spinal cord, is crucial for coordinating postural preparation with step initiation. To investigate the feasibility of vibrotactile feedback in restoring PSI and overcome step initiation failure in PD+FOG.
Details
Title
Vibration to restore presynaptic inhibition and alleviate start hesitation in people with Parkinson’s disease and freezing of gait: a study protocol
Creator
Chitlur, Tanisha : Oregon Health and Science University Liu, William : Oregon Health and Science University Boari, Daniel : Federal University of ABC Horak, Fay B. : Oregon Health and Science University Mancini, Martina : Oregon Health and Science University Silva-Batista, Carla : Oregon Health and Science University
Meeting Name
Research Week, Oregon Health and Science University, 2023
