Studying LCHADD chorioretinopathy using a novel LCHADD mouse model
Babcock, Shannon
2024

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Abstract

The goal of this dissertation is to improve understanding and treatment for the chorioretinopathy seen in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) patients by examining the molecular mechanisms and testing potential treatments for LCHADD chorioretinopathy using a novel LCHADD mouse model.

Details

Title Studying LCHADD chorioretinopathy using a novel LCHADD mouse model
Creator Babcock, Shannon : Oregon Health and Science University : (0000-0003-2365-2119)
Contributor Gillingham, Melanie PI (Oregon Health and Science University)
Publisher Oregon Health and Science University
Date 2024-06-13
Subjects
Keywords
DOI https://doi.org/10.6083/bpxhc43378
Language English
Related Resource Is part of: https://doi.org/10.1016/j.ymgme.2024.108351
Is part of: https://doi.org/10.1038/s42003-023-05268-1
Related work citations

1. Babcock, S. J., et al. (2024). "A review of fatty acid oxidation disorder mouse models." Mol Genet Metab 142(1): 108351.

2. Gaston G, Babcock S, Ryals R, Elizondo G, DeVine T, Wafai D, Packwood W, Holden S, Raber J, Lindner JR, Pennesi ME, Harding CO, Gillingham MB. A G1528C Hadha knock-in mouse model recapitulates aspects of human clinical phenotypes for long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. Commun Biol. 2023 Aug 29;6(1):890. doi: 10.1038/s42003-023-05268-1. PMID: 37644104; PMCID: PMC10465608.

Content Type Dissertation
Degree Type Ph.D.
Academic Program Molecular & Medical Genetics
Department Department of Molecular and Medical Genetics
School School of Medicine
Grant Information National Eye Institute
Copyright Status
Usage Statement
Record ID 43378
Record Created 2024-06-13
Record Appears in Organizations > Departments and Divisions > School of Medicine Basic Sciences Departments > Department of Molecular and Medical Genetics
OHSU Works > Student Work > Academic Programs > School of Medicine Programs > Molecular & Medical Genetics
OHSU Works > Student Work > Degrees > Doctor of Philosophy (Ph.D.)
Organizations > Schools > School of Medicine
OHSU Works > Student Work > Dissertations
Theses and Dissertations
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