Association between plasma PCSK9 levels and computed topographic coronary artery calcium
Mahmood, Tahir; Minnier, Jessica; Miles, Joshua; Warden, Bruce; Fazio, Sergio; Shapiro, Michael D.
2020

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Abstract

Given its central role in low-density lipoprotein (LDL) metabolism, there is interest in exploring proprotein convertase subtisilin/kexin type 9 (PCSK9) as a potential circulating biomarker of atherosclerotic cardiovascular disease (ASCVD) risk. Computed tomography for coronary artery calcium (CAC) scoring provides an accurate assessment of subclinical coronary atherosclerotic plaque burden and can be used to refine cardiovascular risk estimates in individuals without symptoms of ASCVD. In this study, we assessed the correlation of cross-sectional measurements of plasma PCSK9 concentration and CAC score in individuals free of clinical ASCVD.

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Title Association between plasma PCSK9 levels and computed topographic coronary artery calcium
Creator Mahmood, Tahir : Oregon Health and Science University
Minnier, Jessica : Oregon Health and Science University
Miles, Joshua : Oregon Health and Science University
Warden, Bruce : Oregon Health and Science University
Fazio, Sergio : Oregon Health and Science University
Shapiro, Michael D. : Oregon Health and Science University
Meeting Name Research Week, Oregon Health and Science University, 2020
Publisher Oregon Health and Science University
Date 2020
Subjects
Keywords
DOI https://doi.org/10.6083/5d86p096x
Content Type Abstract
Department OHSU Knight Cardiovascular Institute
Copyright Status
In copyright - joint owners
Usage Statement
Record ID 8326
Record Created 2023-06-29
Record Appears in Organizations > Centers and Institutes > OHSU Knight Cardiovascular Institute
OHSU Works > Events > Research Week
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