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Interferon (IFN) family cytokines stimulate a broad group of genes known as interferon stimulated gene (ISGs). The primary function of ISGs is to provide antiviral host d [...]

The field of microbiome research has grown exponentially in both popularity and importance over the past decade. Microbiome data consists of highly dimensional and comple [...]

The gut microbiome is involved in promoting or inhibiting (protecting against or contributing to the development of) many diseases, such as diabetes, inflammatory bowel d [...]

Color Vision Deficiency (CVD), commonly called colorblindness, is estimated to affect 300 million people worldwide, which is comparable to the most recent US population e [...]

Ankylosing​ ​spondylitis​ ​(AS)​ ​is​ ​a​ ​chronic​ ​inflammatory​ ​disorder​ ​in​ ​which​ ​aberrant immune​ ​responses​ ​to​ ​the​ ​intestinal​ ​microbiota​ ​are​ ​thoug [...]

The field of microbiome research has grown exponentially over the past decade, marked by substantial investments in resources and recognition of its potential clinical si [...]

We developed a workflow for quantitative microbiome profiling to quantify bacterial abundance using a known mock microbial dilution series.

Recently, longitudinal changes in human gut microbiome composition have been proposed to be more robust markers of host health than cross-sectional variation. However, it [...]

Here we evaluated the accuracy of several freely available software packages to correct for variable gene copy numbers in microbiome profiling using the 16S rRNA gene. We [...]

There is growing appreciation for the role that commensal microorganisms play in affecting host health and disease, especially in humans. Comprised of bacteria, fungi, vi [...]