Obesity is a global health concern linked to chronic diseases such as diabetes, hypertension, and cancer, yet its underlying mechanisms remain unclear. Conjugated linolei [...]

Age related sleep disruption and fragmentation are common in elderly populations and the amount of time spent in rapid eye movement (REM) sleep naturally declines with ag [...]

Vitamin E protects cell membranes from oxidative damage, and vitamin C helps regenerate vitamin E, enhancing its antioxidant effect. Smoking increases oxidative stress, r [...]

Regardless of oxygen availability, Bacillus subtilis is able to survive by maintaining highly regulated and coordinated metabolic pathways, with activation or repression [...]

Inherited disorders of long‑chain fatty acid oxidation (FAO) impair the ability to use long‑chain fatty acids for energy, making exercise risky due to potential rhabdomyo [...]

Spx is a global transcriptional regulator in Bacillus subtilis that mediates oxidative stress responses through interactions with the RNA polymerase α subunit C-terminal [...]

The greatest risk factor for developing Parkinson's disease is aging, and the accumulation of reactive oxygen species is thought to play a significant role in the aging p [...]

Lewy bodies comprised of aggregated alpha synuclein (αSyn) protein are a pathological hallmark of the Parkinson's disease (PD). Increased oxidative stress, mitochondrial [...]

Bacillus subtilis Spx is a global transcriptional regulator that is conserved among gram-positive bacteria, in which Spx is required for preventing oxidatively induced [...]

Spx, a global transcriptional regulator in Bacillus subtilis, enables oxidative stress survival by activating genes for detoxification and thiol homeostasis. Unlike typic [...]