Rural patients with non–ST-segment elevation myocardial infarction (NSTEMI) often present to local hospitals that lack cardiac revascularization capability, necessitating [...]

This thesis focuses on acid‑sensing ion channels (ASICs), with particular attention to their mechanisms of activation and desensitization. ASICs are proton‑gated ion chan [...]

Functional microcirculation—intact, RBC‑perfused vessels—is essential for delivering oxygen and nutrients to tissues, and its disruption is a hallmark of many diseases. T [...]

White matter injury (WMI) contributes substantially to neurological impairment after ischemic stroke. However, WMI is often ignored in stroke therapeutic developments lea [...]

This dissertation aims to address how ischemic injury induces cerebrovascular dysfunction and triggers a pathological cycle to accelerate the onset and progression of Alz [...]

Sympathetic nerves are lost in the damaged myocardium (infarct) after myocardial infarction (MI), and the relative area of denervation predicts risk of sudden cardiac arr [...]

Errors in the management of self medication in the home environment are not unusual. The occurrence of potentially serious medication errors can be documented by talking [...]

This research investigates two novel therapeutic strategies for ischemic stroke: osteopontin (OPN)–based neuroprotection and thyronamine-induced hypothermia. OPN was show [...]