This novel computational framework for the analysis of single-cell gene expression data from human tumor samples enables the identification of molecular activity associat [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

Immune checkpoint inhibitors have shown success in treating a subset of patients with certain late-stage cancers. However, these treatments fail in many other patients, d [...]

I have developed a co-mutation frequency network to infer functional redundancy between pairs of cancer genes. This analysis builds on previous work that leverages mutual [...]