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Mechanisms of immune suppression in peripheral tissues counteract protective immu-nity to prevent immunopathology and are coopted by tumors for immune evasion. Blood and [...]
2019 | Dissertation |
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Tissue-resident memory T cells (TRM) are enriched in nonlymphoid barrier organs where they typically reside long-term without recirculating. These cells are functionally [...]
2024 | Abstract |
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Breast cancer is a leading cause of illness and death among women in the United States, being the second most common cancer after non-melanoma skin cancer. It is also the [...]
2013 | Thesis |
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This thesis describes fibroblast growth factor signaling in the development of resistance to tyrosine kinase inhibitor therapy in solid and hematologic malignancies, and [...]
2016-08-01 | Dissertation |
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Malignant brain tumors remain incurable and improving outcomes will require personalized treatment strategies. In personalized medicine, therapeutics are tailored to each [...]
2019 | Dissertation |