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Colorectal cancer is one of the most pervasive and deadly diseases in the world today. Although heavily studied with a wealth of available scientific data, little resear [...]

This novel computational framework for the analysis of single-cell gene expression data from human tumor samples enables the identification of molecular activity associat [...]

Despite their devastating impacts on millions of people, most rare and congenital disorders remain poorly understood, leaving the patients with these disorders with no FD [...]

Cells in vivo are continuously exposed to a range of small messenger proteins (microenvironmental ligands). Microenvironmental ligands bind to cell-surface receptors and [...]

Allogeneic hematopoietic cell transplantation (allo HCT) is the only curative therapy for patients with intermediate-2 or high risk myelofibrosis (MF). We sought to exami [...]

Color photographic portrait of Reid S. (Sam) Connell, Ph.D., Emeritus Professor, Cell & Developmental Biology, OHSU Vice Provost for Allied Health's?

During development, cells must migrate from their origin to their final destination, a process that is dependent on the actin cytoskeleton. Cells can migrate independentl [...]

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Black and white photograph of Reid S. (Sam) Connell laughing with two colleagues as he receives or hands out a flower.